Freeze-dried timing and freeze-drying curve

by:CBFI     2020-10-11
Freeze-dried timing and freeze-drying curve is introduced:

freeze-drying curve is freeze-drying chamber plate layer relation curve between temperature and time. The abscissa denotes the average temperature as the ordinate, time. It reflects the lyophilization process, the changes of the different time plate layer temperature. Freeze-dried sequence is different time in the process of freeze-drying, all kinds of opening and closing operation of the equipment.

freeze-dried timing and freeze-drying curve of contact:

freeze-drying curve and freeze-dried sequence is not only the manual operation of the lyophilizer basis, but also the basis of automatic control of the lyophilizer operation. For example, using the method of CAM and roller method for automatic control of the lyophilizer, score basis of CAM and roller is freeze-drying curve and timing, when using microprocessor to control the lyophilizer, the compilation basis and freeze-drying curve and timing of the operation procedures, in accordance with the requirements for microcomputer of the freeze-drying curve and timing within the reservoir with microcomputer keyboard input.

freeze-dried importance sequence and freeze-drying curve:

biological products of freeze drying products, need to have a certain physical form; Uniform color, the residual water content of qualified, good solubility, high survival rate, or titer, long shelf life. Therefore, not only to the process of seedlings and sealed after lyophilization. What is more important for the parameters of the freeze drying process of each stage to conduct a comprehensive control, can obtain the high quality products. Freeze-dried freeze drying curves and time sequence is the basic foundation of process control.

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